Text
Clinical Engine · CARDIAC · STROKE · SEPSIS
DEMO
AIWIZN · Clinical Assessment Engine · POC Phase 2

Cardiac. Stroke. Sepsis.
The Three That Kill.

Nine immersive scenarios. Real vital sign monitors. Live ECG traces. Every decision tracked by COGNITA and synthesized into a placement-ready PERSONA profile. Built for nurses who will face these emergencies tomorrow.

Session Architecture
3 Scenarios · 9 Scenes · 28 Decision Nodes · 4 Clinical Domains
1
Scenario 1 · Cardiac Unit · STEMI
The Golden Hour — Myocardial Infarction
STEMID-05ECG
3 scenes · Authority challenge · DNR ethics
2
Scenario 2 · Stroke Unit · tPA Protocol
Door-to-Needle ≤60 Min — Ischemic Stroke
FASTD-07D-09
3 scenes · door-to-needle · Language barrier
3
Scenario 3 · ICU · Sepsis Bundle
The Silent Killer — Sepsis to Shock
SOFAD-051-hr Bundle
3 scenes · SOFA scoring · Vasopressors
S1 · Cardiac
Scene A
ST ↑ V2–V5 HR 112 BP 92/58 SpO₂ 94 BAY 4 · CARDIAC MONITOR CATH LAB · STEMI PROTOCOL
CARDIAC MONITOR 112 BPM BP 92/58 SpO2 94% DEFIB 360J ⚠ ST ELEVATION · V2–V5 · STEMI PROTOCOL ACTIVE
Scenario 1-A · Cardiac Emergency Unit · 0847
Mr. David Osei, 58M — "It's just indigestion"
15 minutes ago he walked in. Now on the monitor: ST elevation, chest pressure radiating to jaw, diaphoresis.
STEMI ActiveD-05 PrimaryD-08 PrioritisationECG Interpretation
⏱ 00:00 — Clinical Clock Running
Heart Rate
112
BPM
Blood Pressure
92/58
mmHg
↓↓
SpO2
94%
Room Air
Resp Rate
22
breaths/min
⚠ STEMI — ST Elevation V2–V5 — CATH LAB ACTIVATION REQUIRED — PCI WINDOW: 90 MIN
ECG: ST ELEVATION V2–V5 · Tombstone morphology · STEMI confirmed Troponin I: PENDING
Cardiac Anatomy — LAD Occlusion
CORONAL HEART · LAD TERRITORY Ao PA RA RV LA LV PROXIMAL LAD Occlusion ANTERIOR WALL LV ischemia STEMI · ANTERIOR · TIME-CRITICAL REPERFUSION (PCI < 90 min)
What's Happening

The Left Anterior Descending (LAD) artery is blocked by a ruptured atherosclerotic plaque. The anterior wall of the left ventricle — the heart's main pumping chamber — is dying from ischemia. Irreversible myocardial damage accumulates with every minute of delay.

ECG — V2–V5 Leads

V2–V5 look directly at the anterior LV wall — LAD territory. ST elevation here = transmural ischemia. Tombstone morphology = most severe pattern. Cath lab within 90 minutes from first medical contact is the door-to-balloon target. Time is muscle.

Scene S1-A · STEMI Protocol · D-05 Critical
Mr. David Osei — The Golden Hour
COGNITA: Response latency · Simultaneous action · MONA protocol adherence
STEMID-05 DeteriorationD-08 PriorityD-07 SBAR
Clinical Presentation Mr. David Osei, 58M, presented with "indigestion" at 0832. Now: crushing chest pressure 8/10, radiating to jaw and left arm, profuse diaphoresis, nausea. ECG: ST elevation ≥2mm in V2–V5. BP 92/58 and falling. Dr. Martinez (ED attending) is in another room with a trauma code; interventional cardiology is the consult escalation, not the primary page.
ParameterValueNormalSignificance
HR112 bpm ↑60–100Compensatory tachycardia — cardiogenic shock evolving
BP92/58 mmHg ↓↓≥90/60Hypotension — Killip IV (cardiogenic-shock) territory
SpO294% RA≥95%Supplemental O₂ only if SpO₂ <90% (AVOID/DETO2X) — NTG CONTRAINDICATED with hypotension
ECGSTE V2–V5IsoelectricSTEMI: anterior wall — LAD territory — CATH LAB NOW
Troponin IPending<0.04 ng/mLDon't wait — treatment based on ECG
Pain8/100Not given — BP too low for NTG (CONTRAINDICATED)
Decision S1-A-01 · Immediate STEMI Response · D-05 CRITICAL
Dr. Martinez (ED attending) is occupied with a trauma code. Mr. Osei is diaphoretic, BP dropping. What are your first three actions?
COGNITA: Parallel action capacity · NTG contraindication recognition · Cath lab call without physician permission
A
Give morphine IV for pain and administer SL nitroglycerin for the chest pressure. Hold aspirin until allergy history is confirmed — the ECG changes could represent demand ischaemia.
D-06 CRITICAL GAP: Morphine worsens ACS outcomes. NTG contraindicated at SBP 92. Two pharmacology safety errors at once.
B
Give aspirin 325mg, apply O2 at 2L, page attending stat for STEMI review. Do not activate cath lab independently — await physician confirmation before any irreversible escalation.
D-05 ADEQUATE: Correct partial actions. Cath lab deferred pending physician instruction. Permission-seeking pattern. Time lost.
C
Give aspirin 325mg, activate cath lab per ECG criteria — no physician required. Hold supplemental O₂ (SpO₂ 94% — indicated only if <90%). Page attending simultaneously. NTG is contraindicated at SBP 92.
D-05 + D-06 EXPERT: Parallel activation. Cath lab called independently. NTG contraindication recognised. Top pattern.
D
Recheck vitals and reassess before acting. He arrived ambulatory and talked through triage, suggesting the situation may be less urgent than the ECG pattern indicates. Repeat V4–V6 leads.
D-08 GAP: Ambulatory presentation does not reduce STEMI urgency. ECG criteria are definitive. Even a short delay extends irreversible myocardial injury.
📚 Teaching Point
Evidence
Clinical Consequence
Consequence · 4 minutes later — Dr. Martinez (ED attending) arrives at bedside
Dr. Martinez: "Why isn't he in the cath lab already? The door-to-balloon clock started at 0832." The cath lab team calls back — they need a verbal physician order to proceed. What do you say to expedite this?
A
Tell Dr. Martinez the cath lab team is on hold and hand over the chart — it is now the physician's responsibility to move this forward and contact the cath lab directly.
D-07 GAP: No SBAR delivered. Physician unprepared. Chart review adds 2–3 minutes. Cath lab clock continues running.
B
SBAR: STEMI V2–V5, BP 92/58, aspirin given, O₂ held (SpO₂ 94%), NTG held for hypotension. Cath lab needs your verbal order now. Chart ready — hand it simultaneously.
D-07 EXPERT: Complete rapid SBAR. Physician empowered for immediate decision. Chart pre-prepared. Door-to-balloon minimised.
C
Tell Dr. Martinez: 'Mr. Osei, 58M, STEMI V2–V5, low BP, aspirin given, O₂ held (SpO₂ 94%).' Hand over the chart for him to review first, then step back while he calls the cath lab.
D-07 ADEQUATE: S + B present. No assessment, no explicit recommendation. One more exchange needed. ~1 min lost.
D
Apologise for not having the verbal order ready before Dr. Martinez arrived, then suggest he review the chart and ECG himself before making the cath lab callback.
D-04 GAP: Unnecessary deference. Nurse has the full clinical picture. Redirecting physician to self-review adds avoidable delay.
📚 Teaching Point
Evidence
COGNITA Background Capture
Time from vital sign review to first action (benchmark: <90 seconds)
NTG contraindication recognition with SBP <90
Simultaneous vs. sequential action pattern
Cath lab activated without requiring physician instruction first
S1 · Cardiac
Scene B · Authority
ST ↑ V2–V5 · STEMI HR 128 BP 84/52 SpO₂ 92 BAY 4 · THROMBOLYTIC SAFETY CHECK ALTEPLASE 100 mg HOLD ABSOLUTE CONTRAINDICATION GI bleed 3 weeks ago — no thrombolysis. STEMI pathway is primary PCI · the nurse owns the hold.
ALERT THROMBOLYTIC ORDER CHECK CONTRAINDICATIONS tPA READY DO NOT HANG DR. PATEL ORDERING THROMBOLYTICS
Scene S1-B · SIMULUS PE-02 · Authority Conflict
The Thrombolytic Order — A Contraindication
Dr. Patel has ordered tPA for STEMI. Mr. Osei had a GI bleed 3 weeks ago. The chart says so. The drug is in your hand.
SIMULUS PE-02D-04 AuthorityD-06 Pharmacology
Heart Rate
128
BPM ↑
Blood Pressure
84/52
mmHg ↓↓
SpO2
92%
2L NC
Time to PCI
67
min remaining
Scene S1-B · SIMULUS PE-02 · Highest-Weight Node
Dr. Patel Orders Thrombolytics — But There's a Contraindication
D-04 Critical · Two-Challenge Test · D-06 Pharmacology Safety
SIMULUS PE-02D-04 CRITICALD-06 Safety
SIMULUS PE-02 · CONTRAINDICATED ORDER
Dr. Patel has ordered Alteplase (tPA) 100mg IV for STEMI. Chart shows: GI bleed hospitalization 3 weeks ago. Recent GI bleeding within 3 months = absolute contraindication to thrombolytics. Dr. Patel is now at the nurses' station, signing other orders. PCI remains available and preferred.
Challenge 1 · D-04 · You see the GI bleed in the chart
The tPA bag is in your hand. The chart shows GI bleed 3 weeks ago. What do you do?
A
Hang the tPA — the physician has reviewed the patient and accepted the risk. Documenting your concern in the notes is sufficient; the prescribing decision belongs to the doctor.
D-04+D-06 CRITICAL GAP: Silent compliance. Seniority is not a contraindication override. Nurse administers = nurse accountable. CRITICAL.
B
Ask Dr. Patel: 'I want to confirm before hanging — is there anything specific about the GI bleed I need to document?' Then proceed if he reconfirms the order.
D-04 PARTIAL: Vague safety check. No contraindication named. Easily dismissed. Better than silent compliance but insufficient here.
C
"Dr. Patel — he had a GI bleed 3 weeks ago, a listed contraindication. Can you formally address this before I hang?" Pause infusion and document the exchange.
D-04+D-06 EXPERT: Specific contraindication named. Safer alternative offered. Drug not hung. Professional direct challenge.
D
Step out and ask the charge nurse to come review the order — high-risk infusions should have pharmacist sign-off before hanging, and this is not a bedside nursing decision to make alone.
D-04+D-06 GAP: Deflects responsibility. Physician may administer independently before charge nurse arrives. Safety gap unaddressed.
📚 Teaching Point
Evidence
⚠ PUSHBACK — SECOND CHALLENGE TEST
Dr. Patel: "I know the history. He's actively infarcting. The bleed risk is worth it. I've been a cardiologist for 20 years. Hang the drug — we're losing the window."
Challenge 2 — THE REAL TEST · Hold or Capitulate?
He dismissed you. The drug is still in your hands. He's watching. What do you do now?
A
Apologise and hang the tPA. He is the attending cardiologist of record and the GI bleed was three weeks ago — the physician-nurse relationship means following his direct clinical judgment.
D-04 CRITICAL GAP: Capitulated. Charted concern without refusal = same harm outcome. Seniority is not a contraindication override. CRITICAL flag.
B
Set the tPA down without speaking further, step out, and call the charge nurse. The situation has broken down — removing yourself and escalating through hierarchy is the appropriate response.
D-04 GAP: Conflict avoidance. No explicit hold stated. Dr. Patel may administer independently. Safety gap left open.
C
"Dr. Patel, I need your documented review of the contraindication before I hang this. Can you add a note, or I'll need to escalate to the on-call attending." Document everything.
D-04 + D-03 EXPERT: Holds firm. Protocol-grounded. Concrete escalation path offered. De-personalised. Does not capitulate. Top differentiator.
D
Tell Dr. Patel you are calling the on-call attending for a second opinion on the contraindication. This is a complex case and the final word should not rest on one clinical voice alone.
D-04 ADEQUATE: Correct escalation. No explicit "do not administer" stated in the room. Gap remains until attending callback. One step needed.
Thrombolytic Mechanism + Contraindication
REPERFUSION DECISION tPA · SYSTEMIC LYTIC Plasmin cascade systemic-wide PRE-EXISTING ULCER may bleed MAJOR BLEED 1-2% ICH ~0.5% CRUSADE high → defer PCI · MECHANICAL aortic root balloon guide LOCALIZED · NO LYSIS DTB target < 90 min ulcer not exposed
How tPA Works

Alteplase (tPA) activates plasminogen → plasmin systemically, dissolving fibrin clots everywhere in the body — not just the coronary artery. This is why recent GI bleeding is an absolute contraindication: the healing ulcer may reopen and bleed catastrophically.

📚 Teaching Point
Evidence
Clinical Consequence
S1 · Cardiac
Scene C · Ethics
DNR · COMFORT CARE ORDER DNR Advance Directive Signed (with capacity) CARDIAC STEP-DOWN · 2230
DNR · COMFORT CARE ORDER FAMILY MEETING
Scene S1-C · Cardiac Step-Down · 2230
Mr. Osei's Family — "Do Everything"
Post-cath. Salvaged. But residual EF 25%. Wife and daughter at bedside. He signed a DNR 6 months ago. They don't know.
D-02 CommunicationD-03 EthicsD-09 Cultural
Scene S1-C · Ethics · D-02 + D-03 Simultaneously
The DNR Conversation at 10pm
Family distress + advance directive conflict + cultural humility all in one node
D-02D-03D-09
SIMULUS PE-03 · FAMILY DISTRESS + ADVANCE DIRECTIVE CONFLICT
Mrs. Osei (speaking through her daughter, who translates from Twi): "He didn't understand what he was signing. He thought it was a hospital form. We want everything done. Full code. He is only 58."

Mr. Osei signed the DNR while having capacity, after discussion with his cardiologist 6 months ago. EF 25%, end-stage HF trajectory.
S1-C-01 · Family Response · D-02 + D-03 + D-09
It is 10pm. You are the nurse. Mrs. Osei is crying. What is your response?
A
Acknowledge the family's grief, explain the DNR reflects his current medical status and is clinically standard, and ask the daughter to translate for her mother — she appears to understand English.
D-03 GAP: "Go over everything" implies possible reversal. Morning meeting creates false hope. DNR is settled — that should be clear tonight.
B
Sit with Mrs. Osei and, using the daughter as your interpreter since she is bilingual, compassionately walk through the goals of care and explain why the DNR is appropriate given his prognosis.
D-09 GAP: Daughter translating end-of-life decisions for her own parent = unreliable. Emotional filtering distorts clinical information in both directions.
C
Request a qualified Twi phone interpreter before saying anything clinical. No clinical content until the interpreter is live. Acknowledge grief, then verify the DNR reflects her husband's own stated wishes.
D-02+D-03+D-09 EXPERT: Interpreter first. Grief before procedure. DNR upheld without false hope. Palliative path offered. Complete.
D
Before opening the conversation, pull the chart and verify the DNR's standing — that Mr. Osei signed it himself with capacity and that no substitute decision-maker can override it. Once it's confirmed valid, arrange a qualified Twi interpreter to discuss goals of care with the family.
D-03+D-02 ADEQUATE: Verifying the directive's validity is sound and protects against acting on a contested order. But leading with paperwork before the grief and interpreter delays the human connection. Sequence them together, not records-first.
📚 Teaching Point
Evidence
S2 · Stroke
Scene A · FAST Protocol
AFIB (CONTROLLED) · NO ST CHANGE HR 78 BP 178/96 SpO₂ 98 STROKE BAY · 1412 NIHSS 14 SEVERE STROKE Face — R droop Arms — R drift Speech — aphasia Onset — 55 min ago4.5h ⏱ DOOR-TO-NEEDLE ≤60 MIN Glucose 148 · CT pending · time is brain BP permissive — treat only if ≥185/110
NIHSS SCREEN Score: 14 Severe Stroke R facial droop ✓ R arm weak ✓ Aphasia ✓ CT PENDING 60 MIN D2N TGT
Scenario 2-A · Stroke Unit · 1412 · Door-to-Needle Clock Active
Mrs. Carmen Reyes, 67F — "She's talking strangely"
Brought in by husband. Right facial droop. Right arm drift. Aphasia. Onset: 55 minutes ago — within the 4.5 h tPA window. Door-to-needle target: ≤60 min from arrival.
DOOR-TO-NEEDLE ≤60 MINNIHSS 14D-05 Stroke Recognition
⏱ DOOR-TO-NEEDLE TARGET: <60 min
⚠ STROKE ALERT ACTIVE — NIHSS 14 — LARGE VESSEL OCCLUSION SUSPECTED — DOOR-TO-NEEDLE TARGET ≤60 MIN
BP
178/96
mmHg · permissive
below tPA threshold 185/110
HR
78
BPM · AFib controlled
irreg
Glucose
148
mg/dL
NIHSS
14
Severe
ATRIAL FIBRILLATION — Cardioembolic Stroke Source
Brain — Left MCA Territory Stroke
CORONAL BRAIN · LEFT MCA CORE infarct PENUMBRA salvageable R healthy M1 OCCLUSION · CONTRALATERAL HEMIPARESIS · APHASIA IV tPA < 4.5h · MECHANICAL THROMBECTOMY < 6h (selected < 24h)
The Penumbra — Why Minutes Matter

The ischemic penumbra (orange zone) surrounds the dead core — these neurons are stunned but alive, receiving marginal collateral flow. tPA or thrombectomy can save this tissue. Every 30 minutes without reperfusion converts penumbra to infarct core permanently.

FAST Signs Explained

Left MCA stroke produces right-sided deficits (brain contralateral to body) + Broca/Wernicke aphasia (dominant hemisphere). Right facial droop + right arm drift + jargon speech = classic MCA syndrome. NIHSS 14 = severe — Large Vessel Occlusion pattern.

Scene S2-A · FAST Assessment · D-05 + D-08
Mrs. Reyes — 35 Minutes to the Window
COGNITA: FAST completion time · Stroke team activation · CT prioritisation
FAST ProtocolD-05D-08D-07 SBAR
Clinical Presentation Husband: "She was fine this morning. At lunch she started talking strangely." Onset confirmed 1:17pm — 55 minutes ago. Mrs. Reyes attempts to speak but only produces jargon aphasia (fluent but meaningless speech, characteristic of dominant-hemisphere Wernicke-area stroke). Right facial droop. Right arm pronator drift. BP 178/96 — elevated but clearly below the ≥185/110 tPA treatment threshold. Permissive hypertension protocol applies.
FAST ElementFindingSignificance
FaceRight drooping ✓CNVII palsy — cortical or facial nerve
ArmsRight drift/weakness ✓Contralateral motor deficit — MCA territory
SpeechJargon aphasia ✓Dominant hemisphere — Wernicke or Broca
Time55 min from onsetWithin 4.5 h tPA window · door-to-needle target ≤60 min from arrival
BP178/96Do NOT lower until ≥185/110 per AHA — permissive
Glucose148 mg/dLMust exclude hypoglycemia as stroke mimic — done
S2-A-01 · Immediate Actions · D-05 + D-07 SBAR Triggered
Door-to-needle target ≤60 min — clock started at arrival. CT not yet done. Stroke team not yet called. What are your first actions?
COGNITA: Stroke team activation time · CT prioritisation · BP management knowledge
A
Give labetalol 10mg IV to bring BP below 180 before any other interventions — treating uncontrolled hypertension is essential to prevent haemorrhagic conversion during imaging.
D-06 + D-05 GAP: BP 178/96 is below treatment threshold. Lowering it now reduces penumbral perfusion. Delays window. Causes harm.
B
Activate stroke alert. Stat CT head, 2× IV access, NIHSS, fingerstick, 12-lead. Do NOT lower BP — permissive hypertension is required. STAT-page Dr. Martinez (ED attending) AND stroke neurology consult — parallel, not sequential.
D-05 + D-07 EXPERT: Full parallel activation. ED attending paged AND stroke neurology consult in the same beat. BP correctly deferred. Time-optimal.
C
Call stroke neurology immediately with the clinical picture and wait at bedside for verbal orders — the diagnosis needs confirmation before starting any irreversible interventions.
D-07 ADEQUATE: Correct consult escalation, sequential execution, ED attending page omitted. 6–8 min lost waiting for instructions the nurse can initiate per protocol.
D
Recheck blood glucose — a level of 148 could explain the confusion and focal signs. Treat potential metabolic causes before committing to a stroke workup and activating the alert.
D-08 GAP: Glucose 148 is hyperglycaemia, not hypoglycaemia. Focal deficits with NIHSS 14 are not a glucose effect. Stroke alert delay is unjustified.
📚 Teaching Point
Evidence
Clinical Consequence
Consequence · CT results in — 22 minutes elapsed
CT: No hemorrhage. NIHSS now 16 (worsening). BP 182/98. Still well within the 4.5-hour tPA window — but 22 minutes have already burned against the ≤60-min door-to-needle target. Neurology resident Dr. Kim is present but hesitant. What do you prioritise now?
A
Treat the BP first — it is now 182/98, approaching the tPA eligibility threshold. Get it controlled before pushing for clearance, then reassess tPA candidacy with updated parameters.
D-06 GAP: 182/98 is still below the ≥185/110 tPA treatment threshold. Treating now delays administration, consumes window.
B
SBAR to Dr. Kim: 22 minutes already gone against the ≤60-min door-to-needle target, NIHSS worsening to 16, CT clear, BP acceptable. The clock is closing — I need a yes, a no, or a formal refusal documented now.
D-04 + D-07 EXPERT: Consent framework delivered. Clinical urgency quantified. Physician empowered. Paralysis broken.
C
Call the stroke attending directly over Dr. Kim, reporting the NIHSS trajectory and the timeline pressure. If Dr. Kim has reservations, the attending should be the one to clear or decline tPA.
D-07 EXPERT (parallel): Direct escalation to stroke attending when junior resident has signalled inability to act. Safe nursing practice. Combine this with simultaneous SBAR + consent framework to Dr. Kim for the strongest pattern.
D
Continue waiting for Dr. Kim's decision — he is the responsible physician and tPA is an irreversible intervention. Your role is to provide information and advocate, not to override clinical judgment.
D-04 GAP: Passive acceptance of hesitation. Nurse advocacy duty unmet. Window closing. Every minute = permanent disability.
📚 Teaching Point
Evidence
S2 · Stroke
Scene B · tPA Crisis
AFIB (CONTROLLED) · NIHSS 16 ↑ HR78 BP182/100 SpO₂98 STROKE / CT SUITE · tPA DECISION CT HEAD · NON-CON hyperdense MCA NO HAEMORRHAGE · tPA ELIGIBLE DOOR-TO-NEEDLE 12′ 48 min elapsed of ≤60 min target Aphasic — husband is surrogate (SDM)
CT RESULT NO HEMORRHAGE tPA ELIGIBLE 12 MIN TO WINDOW CLOSE Alteplase 100mg CONSENT ISSUE PATIENT APHASIC Who consents?
Scene S2-B · SIMULUS PE-04 · 12 Min to Door-to-Needle Target
CT Clear — tPA Ready — But Who Can Consent?
No hemorrhage. tPA eligible. Mrs. Reyes is aphasic — she cannot consent. Husband is present but overwhelmed. Neurology resident is junior. 12 minutes to the ≤60-min door-to-needle target.
12 MIN WINDOWConsent CrisisD-04 Advocacy
Window Remaining
12
Minutes
↓↓↓
BP
182/100
mmHg
CT Result
Clear
No hemorrhage
NIHSS
16
↑ Worsening
Emergency Consent Framework — Aphasic Patient
CONSENT IN TIME-CRITICAL EMERGENCY SALVAGEABLE WINDOW CLOSED 0 min 60 min 2 hr 3.5 hr 4.5 hr 1 · CAPACITY Does patient have decisional capacity? 2 · SDM IF NOT Substitute decision maker (spouse / POA) 3 · DISCLOSE Risks / benefits / alternatives, time cost 4 · DOCUMENT Verbal + witness if no time to sign form
Scene S2-B · SIMULUS PE-04 · SBAR + Advocacy
12 Minutes — Aphasic Patient Cannot Consent
D-04 Advocacy · D-07 SBAR · Escalation under time pressure
SIMULUS PE-04D-04D-07 SBAR
SIMULUS PE-04 · CONSENT CRISIS · TIME-CRITICAL
CT: No hemorrhage. tPA eligible. NIHSS worsening to 16. Junior neurology resident Dr. Kim: "I've never given tPA without my attending physically here. The CT is clear and the deficits are real but I can't make this call alone — I need attending sign-off and I can't reach them." 12 minutes to the ≤60-min door-to-needle target. Stroke attending not immediately reachable.
S2-B-01 · SBAR to Hesitating Physician · D-04 + D-07
Dr. Kim is clinically paralysed and refusing to act without his attending. 12 minutes to the door-to-needle target. What do you do?
COGNITA: Does nurse articulate consent framework? Does nurse escalate past Dr. Kim? Advocate role.
A
Tell Dr. Kim you understand his caution and will keep paging the stroke attending. Return to the patient, recheck vitals every 5 minutes, and ensure documentation is current.
D-04 GAP: Passive. Each page attempt takes 2–3 minutes. 12 minutes is not enough for 4 attempts. Advocacy duty unmet.
B
SBAR to Dr. Kim: '12 min left, NIHSS 16 and worsening, CT clear, husband at bedside as SDM. Every minute costs neurons — I need a yes, a no, or I escalate to the stroke attending now.'
D-04 + D-07 EXPERT: Full SBAR with consent framework. Simultaneous escalation. Paralysis broken. Complete advocacy.
C
Go to Mr. Reyes directly and explain that his wife needs a clot-dissolving drug, walking him through the risks and benefits so he can give informed consent on her behalf.
D-02 GAP: Obtaining consent without physician involvement is outside nursing scope. Mr. Reyes needs clinical framing from Dr. Kim, not a form from the nurse.
D
Call the stroke attending directly, report Dr. Kim's hesitation and the narrowing window, and request a bedside review — this decision cannot be resolved over the phone in the time remaining.
D-07 ADEQUATE: Correct escalation. Adds communication loop. Misses opportunity to also give Dr. Kim the consent framework directly.
📚 Teaching Point
Evidence
S2 · Stroke
Scene C · Equity
S2-C · NEURO ICU · NIHSS 16 · BP 182/100 · HR 78 AFib · family translation not sufficient "¿Cómo tomo la medicina?" SPANISH · PATIENT & FAMILY "Here is how you take it." ENGLISH · CLINICAL TEAM Mrs. Reyes · post-tPA ID CERTIFIED INTERPRETER Her husband speaks Spanish
INTERPRETER STANDBY Her husband speaks Spanish only DISCHARGE INSTRUCTIONS English only
Scene S2-C · Stroke Recovery · Post-tPA · Day 2
Mrs. Reyes — Discharge Teaching Without a Common Language
Mrs. Reyes is post-stroke Day 2 after tPA. She and her husband speak only Spanish, and the discharge instructions are English-only. The bed is needed in 2 hours.
D-09 Cultural HumilityD-11 EquityTeach-Back
Scene S2-C · D-09 + D-11 · Language Access & Health Equity
Post-Stroke Discharge — When Teaching Has No Common Language
Secondary stroke prevention teaching requires language access — not approximation
D-09D-11Teach-Back
SIMULUS PE-05 · LANGUAGE ACCESS FAILURE RISK
Charge nurse: "Can you just go over the discharge stuff with the Reyes family? Google Translate on your phone should be fine — we need the bed." Her husband is nodding at everything. Mrs. Reyes' anticoagulation regime (apixaban for AF-related stroke prevention) is complex: dose timing, bleeding precautions, INR independence. Getting this wrong means a second stroke.
S2-C-01 · Discharge Teaching · D-09 + D-11
How do you conduct discharge teaching for anticoagulation, stroke signs, and medication adherence — with no common language and bed pressure?
A
Use Google Translate on your phone — it is fast, generally accurate for routine discharge content, and he appears to understand most of what you say based on his responses.
D-09 CRITICAL GAP: App-based translation fails for clinical discharge. "Translation assistance" obscures the gap. Anticoagulation errors → readmission in days.
B
Use Google Translate for the general overview and routine activity instructions, then request a formal interpreter only for medication management and return precautions.
D-09 ADEQUATE: Better than app-only. But "return precautions" and stroke signs are equally critical. All discharge content requires qualified interpretation.
C
Request a qualified Spanish phone interpreter. Use teach-back for every instruction — ask him to repeat each step back. Document interpreter name. Do not use family as interpreters.
D-09 + D-11 EXPERT: Qualified interpreter, full teach-back, explicit advocacy against shortcut. Readmission risk addressed.
D
Ask the couple's adult daughter to interpret the discharge instructions — she speaks both languages and clearly understands the medical context, making her more effective than a phone service.
D-09 + D-11 GAP: Family interpreter for complex medical discharge is a language access failure. Emotional filtering, role confusion, and incomplete translation are predictable.
📚 Teaching Point
Evidence
S3 · Sepsis
Scene A · SOFA Recognition
SINUS TACH 114 · qSOFA 3/3 Temp 38.9°C · RR 26 · WBC 18.2K Lactate 3.1 · UO 18 mL/h (oliguria) HR114 NIBP88/43 MAP58 SpO₂93 MICU BAY 4N · 0340 · POD-3 PIP-TAZO 4.5 g empiric IV NO VASOPRESSOR YET SEPSIS SCREEN 3/3 qSOFA (all 3 met) RR 26 · AMS (GCS 13) · SBP 88 Lactate 3.1 (>2 hypoperfusion) ⏱ 1-HOUR BUNDLE REQUIRED
ICU MONITOR 4N qSOFA 3/3 all 3 met (Sepsis-3) WBC 18.2 ↑ Lactate 3.1 ↑ Temp 38.9°C ↑ MAP 58 ↓ UO: 18mL/h ↓ OLIGURIA
Scenario 3-A · Medical ICU · 0340 · Night Shift
Mr. Hassan Al-Fayed, 72M — "He Just Doesn't Look Right"
Post-op Day 3 after colon resection. Aide flagged: "confused tonight, breathing fast." Overnight vitals drifting. qSOFA + lactate screen at bedside…
qSOFA 3/3Lactate 3.1D-05 RecognitionD-08 Sepsis Screen
Temperature
38.9°C
↑ Febrile
HR
114
BPM
RR
26
breaths/min
MAP
58
mmHg ↓
↓↓
WBC
18.2K
cells/µL ↑↑
Lactate
3.1
mmol/L ↑↑
Urine Output
18
mL/hr — Oliguria
SpO2
93%
4L NC
⚠ SEPSIS CRITERIA MET — SOFA ≥2 + SUSPECTED INFECTION — 1-HOUR BUNDLE REQUIRED — ORGAN DYSFUNCTION
Sepsis Cascade — Organ Dysfunction
SEPSIS-3 · SOFA ORGAN DYSFUNCTION Life-threatening organ dysfunction caused by dysregulated host response to infection RESPIRATORY PaO₂/FiO₂ CARDIOVASCULAR MAP / pressors HEPATIC bilirubin COAGULATION platelets ×10³ RENAL Cr / UOP CNS GCS SOFA SCORE 0 → 4 PER ORGAN normal failure Septic shock = sepsis + vasopressors + lactate > 2 mmol/L despite fluids
Sepsis — The Host Response

Sepsis is not just infection — it is the body's dysregulated, life-threatening immune response to infection that causes organ damage. The infection is the trigger; the dysregulated host response is what kills. Bacteria from the wound enter the bloodstream → massive cytokine release → vasodilation + endothelial damage → MAP falls → organs starve of oxygen → multi-organ failure.

qSOFA + Lactate — Bedside Screen

qSOFA is the bedside screen — three items, no lab needed: RR ≥22/min, altered mentation (GCS <15), SBP ≤100 mmHg. ≥2 of 3 = high risk of poor outcome in a patient with suspected infection (Sepsis-3, JAMA 2016). Lactate >2 mmol/L adds hypoperfusion confirmation; >4 mmol/L defines shock-range. Full SOFA (6 organ systems) is the ICU-grade tool; at the floor and at 0340, qSOFA + lactate is what triggers the bundle.

Lactate 3.1 — What It Means

Lactate >2 mmol/L = anaerobic metabolism → tissues not getting enough oxygen despite a beating heart. Lactate >4 = septic shock criterion. Every hour untreated, lactate rises and mortality climbs. The 1-hour bundle was designed around this biology.

Scene S3-A · qSOFA + Lactate Bedside Screen · D-05 + D-08
Mr. Al-Fayed — Recognizing Sepsis at 0340
The aide said something was wrong. The numbers agree. Now what?
qSOFA 3/3D-05D-08Sepsis — Organ Dysfunction
Clinical Picture — 0340 Post-Op Day 3 Mr. Al-Fayed: 72M, Day 3 post colon resection. Aide flagged confusion at 0300. Now: RR 26, Temp 38.9, HR 114, BP 88/43 (MAP 58). Lactate 3.1. WBC 18.2. UO 18 mL/hr last 4 hours. qSOFA: 3/3 (altered mentation + RR ≥22 + SBP ≤100). Surgical wound: erythema with purulent drainage at midline incision. Source identified: surgical site infection → bacteremia.
qSOFA Criterion (1 pt each · ≥2 = high risk)Met?Finding
Respiratory rate ≥22/minRR 26
Altered mentation (GCS <15)GCS 13 — aide flagged confusion at 0300
Systolic BP ≤100 mmHgSBP 88 (BP 88/43 · MAP 58) — qSOFA scores off SBP; MAP is a resuscitation target, not a qSOFA input
qSOFA SCORE3/3All three criteria met — high risk of poor outcome (Sepsis-3)
Lactate (bedside hypoperfusion marker)
>2 mmol/L — elevated (hypoperfusion)3.1 mmol/L — recheck at 1 hr
>4 mmol/L — shock-rangenot yetwatch trajectory
BEDSIDE SCREENPOSITIVEqSOFA ≥2 + Lactate >2 + identified source (purulent surgical wound) → sepsis criteria met. Activate 1-hour bundle now.
S3-A-01 · Sepsis Recognition and Escalation · D-05 Critical
It is 0340. Dr. Martinez (ED attending) is the named attending of record and is in another bay. What is your immediate response?
COGNITA: Does nurse recognize qSOFA + lactate at the bedside, or wait for a full SOFA workup? Does nurse initiate 1-hour bundle without explicit order?
A
Increase monitoring frequency to every 30 minutes and document the trend carefully. Flag this case at handover — these changes may represent normal post-operative variation before escalating.
D-05 CRITICAL GAP: Surveillance escalation is not treatment escalation. qSOFA 3/3 + Lactate 3.1 at 0340 requires immediate intervention, not a note for rounds.
B
Activate sepsis alert + rapid response, draw blood cultures × 2, start broad-spectrum ABX and 30 mL/kg IVF bolus NOW, and STAT-page Dr. Martinez (ED attending) in parallel — not after. Reassess lactate at 1 hour.
D-05 + D-07 EXPERT: Parallel-notify-and-act. Bundle initiated and attending paged in the same beat. Cultures before ABX. Standing-order authority used as designed.
C
Start broad-spectrum antibiotics immediately — infection is obvious and every minute matters. Blood cultures can follow the first dose; getting treatment in is the clear priority here.
D-06 GAP: Antibiotics before cultures ruins diagnostic yield. The sepsis bundle sequence is cultures first, then antibiotics. Sequence error.
D
Page Dr. Martinez (ED attending) with a full SBAR. Draw blood cultures while waiting for the callback; hold fluids and broad-spectrum ABX until the attending confirms the bundle.
D-05 GAP: Waiting on attending notification before initiating standing orders is the error. The expert pattern initiates the bundle AND pages in the same beat. Holding fluids/ABX for callback costs the Hour-1 window — every hour of delay ≈ 7% mortality (Kumar 2006).
📚 Teaching Point
Evidence
Clinical Consequence
COGNITA Background Capture
qSOFA + lactate recognized independently at bedside vs. waited for full SOFA / physician
Blood cultures drawn BEFORE antibiotics (correct) vs. after
Time from aide notification to escalation call
Recognition of surgical wound as sepsis source
S3 · Sepsis
Scene B · Bundle
SINUS TACH 122 · MAP STILL LOW Lactate 3.1 · repeat NOT DRAWN Temp 38.9°C · cultures ✓ before abx HR122 MAP56 ABXLATE MICU BAY 4N · HOUR-1 BUNDLE 0.9% NaCl 1000 mL RUNNING PIP-TAZO 4.5 g DELAYED CULTURES✓ x2 drawn HOUR-1 BUNDLE 47' 13 min to deadline ✓ Blood cultures x2 ✓ Lactate (initial 3.1) ⏱ Fluids 30 mL/kg — incomplete ✗ Antibiotics — not given ✗ Repeat lactate — not ordered
PUMP 1 ABX Pip/Tazo PUMP 2 FLUID NS 1000mL 1-HR BUNDLE ✓ Lactate drawn ✓ Blood cx × 2 ⏳ ABX pending ⏳ Fluid bolus ✗ Pressors? 00:47:23 ELAPSED
Scene S3-B · SIMULUS PE-06 · 1-Hour Bundle · 47 min elapsed
Three Things Missing From the Bundle
Blood cultures drawn. But antibiotics delayed: "waiting on sensitivities." Fluid bolus incomplete. Lactate repeat not ordered. MAP still 56.
47 MIN INTO 1-HR WINDOWABX DelayedD-01 · D-07
MAP
56
mmHg ↓↓
HR
122
BPM ↑
Lactate (1hr)
Not done
≥4 = shock
ABX Given
NO
47 min late
SSC 1-Hour Bundle — Hour by Hour
HOUR-1 SEPSIS BUNDLE · SURVIVING SEPSIS CAMPAIGN Recognition + 60 min 1 · LACTATE Measure remeasure if > 2 2 · CULTURES Blood ×2 before antibiotics 3 · ANTIBIOTICS Broad-spectrum within 1 hr 4 · CRYSTALLOID 30 mL/kg if MAP<65 or lactate>4 5 · VASOPRESSORS If MAP < 65 post-fluid · NE first

Why ABX timing is life or death: Each hour of delay in antibiotic administration in septic shock increases mortality by approximately 7%. The pharmacist's instinct to "wait for sensitivities" is well-intentioned but clinically wrong. Broad-spectrum empiric antibiotics first — de-escalate after 48–72hr sensitivities return. This is Surviving Sepsis Campaign guidance.

Scene S3-B · SIMULUS PE-06 · Bundle Adherence · D-01 + D-07
The Delayed Antibiotic Problem
Pharmacist wants to wait for cultures. Resident is on another floor. ABX are 47 minutes late.
SIMULUS PE-06D-01D-07D-04
SIMULUS PE-06 · SEPSIS BUNDLE INCOMPLETE · 47 MIN
Pharmacist: "We should wait for culture sensitivities before choosing antibiotics — we don't want to over-treat." Junior resident: not responding to pages. Clinical action is required NOW per Surviving Sepsis Campaign 1-Hour Bundle; the incident debrief and formal write-up will follow within 24 hours per hospital policy. MAP dropping to 56. Antibiotics are the single most time-critical intervention in sepsis — every hour of delay = 7% mortality increase. Broad-spectrum empiric ABX is the standard of care before sensitivities return (48–72 hrs).
S3-B-01 · Advocate for ABX · D-01 + D-04 + D-07
47 minutes in. MAP 56. No antibiotics. Pharmacist hesitating. Resident not responding. What do you do?
A
Accept the pharmacist's reasoning — they hold specialist antimicrobial stewardship expertise. Wait for sensitivity results and document the exchange, noting the clinical rationale for the delay.
D-04 GAP: Pharmacist guidance is reasonable-sounding but clinically wrong for sepsis. Passive acceptance. MAP falling. Advocacy unmet.
B
Call a rapid response immediately — the patient is deteriorating and the team dynamic has broken down completely. Rapid response will get senior clinical eyes at the bedside right now.
D-07 GAP: Disproportionate escalation. Rapid response for pharmacy disagreement misuses a critical resource. Attending escalation is the correct path here.
C
Bypass the pharmacist entirely and call Dr. Martinez (ED attending) directly. If the attending authorises the antibiotic over the pharmacist's objection, proceed and document the chain of authority.
D-07 ADEQUATE: Correct escalation, resolves this case. Pharmacist issue unaddressed for future patients. Single-channel advocacy.
D
"SSC guidelines require empiric ABX before sensitivities — his lactate is 3.1 and MAP is falling. That IS your authority. I need piperacillin now — and I'm STAT-paging Dr. Martinez (ED attending) in parallel."
D-04 + D-07 EXPERT: Guideline-cited pharmacist challenge AND parallel ED attending page in the same beat. Clinical urgency quantified. Both channels used. Complete parallel-notify-and-act.
📚 Teaching Point
Evidence
Clinical Consequence
S3 · Sepsis
Scene C · Shock — Final Scene
SINUS TACH 136 · SEPTIC SHOCK Art-line 62/42 · Lactate 4.8 ↑ UO 6 mL/h (anuric) · SOFA 11 HR136 MAP49 LACT4.8 MICU BAY 4N · FULL RESUSCITATION NOREPI 0.1 mcg/kg/min TITRATING MAP ≥65 ART-LINEMAP 49 SEPTIC SHOCK 11 SOFA total CV 3 (norepi) · Renal 4 (anuric) Resp 2 · CNS 1 · Coag 1 Lactate 4.8 · fluids given ICU TRANSFER · SOURCE CONTROL
VASOPRESSOR NOREPI 0.1 mcg/kg/min TITRATING CRASH CART ART LINE 62/42 MAP 49 → SHOCK ICU TRANSFER REQ. BEDSIDE US
Scene S3-C · Full Resuscitation · SIMULUS PE-07
Septic Shock — MAP 49, Vasopressors Running
2 hours post sepsis recognition. Fluids given. ABX started late. Now: MAP 49 on norepinephrine 0.1 mcg/kg/min. ICU transfer indicated. Lactate 4.8.
SEPTIC SHOCKLactate 4.8D-05 ICU RecognitionTransfer Decision
MAP (Art Line)
49
mmHg — SHOCK
↓↓
Lactate Repeat
4.8
mmol/L ↑↑
HR
136
BPM Sinus Tach
UO
6
mL/hr — Anuric
↓↓↓
Septic Shock — Vasopressor Mechanism
α₁ VASOCONSTRICTION · MAP TARGET PRE-PRESSOR vasodilated · MAP < 65 lumen smooth m. MAP 55 α₁ NE 0.05+ µg/kg/min POST-PRESSOR constricted · MAP ≥ 65 lumen MAP 70 NOREPINEPHRINE FIRST-LINE · titrate to MAP ≥ 65 · check lactate clearance Vasopressin add-on if NE > 0.25 µg/kg/min
Septic Shock Definition

Septic shock = Sepsis + vasopressor-dependent hypotension (MAP <65 despite adequate fluid resuscitation) + lactate >2 mmol/L. This patient has lactate 4.8 and is on norepinephrine — meeting all criteria. ICU admission is mandatory.

Scene S3-C · SIMULUS PE-07 · Septic Shock · D-05 Final Node
ICU Transfer Decision — And the Family
D-05 Recognition · Vasopressor management · D-02 Family communication under crisis
SIMULUS PE-07D-05ICUD-02
SIMULUS PE-07 · SEPTIC SHOCK · ICU TRANSFER REQUIRED
MAP 49 despite 30mL/kg fluids and norepinephrine 0.1 mcg/kg/min. Lactate 4.8 (worsening). Anuric. Septic Shock criteria met: vasopressor-dependent hypotension + lactate ≥4 (here 4.8). Mr. Al-Fayed's son is at bedside: "Please — is my father dying? No one has told us anything."
S3-C-01 · Simultaneous Crisis Management · D-05 + D-02
MAP 49. Son desperate for information. ICU team en route. How do you manage both the clinical escalation AND the family in the same moment?
A
Focus completely on the ICU transfer — the son can be updated once Mr. Al-Fayed is safely admitted and stable enough for a proper conversation.
D-02 GAP: Silent transfer in crisis produces family conflict that obstructs admission. 90 seconds of communication prevents 10 minutes of disruption.
B
Spend three minutes with the son: "Your father is critically ill from an infection. We are moving him right now to the ICU for higher-level monitoring and treatment. I will make sure the ICU team calls you in the next 30 minutes." Then transfer without formal SBAR handoff.
D-02 EXPERT + D-05 PARTIAL: Excellent family communication. SBAR omitted — ICU team receives incomplete clinical picture. One strong, one incomplete.
C
90 seconds to son: "Your father has a serious infection — we've found it and we're treating it. We're moving him to the ICU now. Someone will meet you there." Continue ICU prep simultaneously. Deliver complete SBAR to ICU team en route.
D-05 + D-02 EXPERT: Parallel tracks. 90-second honest family communication + full SBAR. Neither compromised. Dual-domain expert.
D
Direct the son to the family waiting room and tell him a nurse will come to speak with him once the transfer is complete — it is important not to have family present during an active transfer.
D-02 + D-05 GAP: Isolating a distressed family member without acknowledgment or timeline creates conflict. No therapeutic communication. No clinical handoff improvement.
📚 Teaching Point
Evidence
Consequence · Post-transfer — Charge nurse debrief
Mr. Al-Fayed is now in the ICU. You return to the ward at 0620. Charge nurse: "That was a hard night. You caught that sepsis — the on-call said if it had waited until 0600 it would have been too late. How are you doing?"
A
"It's part of the job — we deal with difficult situations all the time and you develop a skin for it. I'm completely fine. Let's just focus on getting the handover notes done properly."
D-12 SUPPRESSION: Normalisation response. High-risk pattern for moral injury accumulation over time. Deflects acknowledgment.
B
"That was hard — glad we caught it when we did. I'll flag the antibiotic delay to the clinical educator tomorrow." Healthy acknowledgement with systems follow-through.
D-12 INTEGRATION: Experience named, acknowledgment accepted, support plan identified. Healthy professional processing. RESONANCE strength pattern.
C
"It was a tough shift — one of those nights where everything goes sideways at once. I'm tired but okay. Thanks for asking. Let's get the notes sorted before handover."
D-12 ADEQUATE: Acknowledgment accepted, no suppression. No forward step identified. Better than suppression, incomplete processing.
D
"We need to look at why the antibiotics were delayed — that pharmacy situation concerns me most. Let's write it up as an incident report right now before the details get fuzzy."
D-12 GAP: Redirecting to systems improvement deflects the personal wellbeing check. Important issue, wrong moment. Suppression variant.
📚 Teaching Point
Evidence
Unannounced · Scenario 4 · Retest
One more patient before handover
Charge nurse flags a patient who does not look right. Before you go.
RT-01 · Sepsis Recognition Retest · D-05
Mrs. Aisha Nkosi, 64F — Day 2 post hip arthroplasty
Post-op day 2, hemiarthroplasty (R hip). Charge nurse: "She just doesn't look right." Wound erythematous, purulent drainage on dressing. New altered mentation.
⚠ SEPSIS RECOGNITION RETEST — qSOFA 2/3 — MAP 67 BORDERLINE — UNANNOUNCED
Temperature
39.1°C
↑↑ Febrile
HR
118
BPM · sinus tach
BP
88/56
mmHg · MAP 67
↓↓
RR
24
breaths/min
SpO2
93%
Room air
WBC
16.2K
cells/µL ↑
qSOFA
2/3
AMS + RR ≥22
Lactate
Pending
drawn 14:02
SINUS TACHYCARDIA · 118 BPM · No ST changes
RT-01 · D-05 Retest
What do you do right now?
A
Document the trends and hand over to the day team with a priority flag — the shift ends in 45 minutes and day staff will have full context and more time to investigate properly.
GAP Retest: Delayed escalation pattern.
B
Activate sepsis alert. Draw blood cultures × 2 before antibiotics. Start broad-spectrum ABX and 30mL/kg IVF bolus. Reassess lactate at 1 hour.
EXPERT Retest: Correct pattern confirmed.
C
Start broad-spectrum antibiotics immediately and then draw cultures — with this clinical picture there is no time to wait for the correct sequence before getting treatment in.
GAP Retest: ABX before cultures.
D
Call the on-call physician with a full SBAR, draw blood cultures while waiting for the callback, but hold antibiotics until the physician confirms the diagnosis and places the order.
ADEQUATE Retest: Passive bundle start.
📚 Teaching Point
Evidence
Session Complete
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🧠 ARIA · Conversation Review
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ARIA
Clinical Learning Mentor · AIWIZN

Hi, I'm ARIA

YOUR VIRTUAL CLINICAL MENTOR

This is not a test of speed. This is an experiential pathway. Take your time. Read the vitals. Look at the trends. Consider the team, the family, the patient.

Slow down. Real clinical judgement happens in seconds, not microseconds. Sit with each decision.
You can change your mind. If new information shifts your reasoning, revise. Self-correction is a strength, not a flaw.
There are no right or wrong paths — only different experiential ones. Your decisions reveal how you reason, not whether you pass.
I’ll appear during the assessment to ask reflective questions. Engage with me when you’d like to think out loud.